HRR Testing in Prostate Cancer

Educational Hub

1.

Precision medicine in prostate cancer, HRR testing

Clinical relevance of testing for HRR mutations in prostate cancer, including BRCA1/2 is multifaceted, with high prevalence of different HRR genetic alterations.

2.

Sample Testing

Different sample types can be used for HRR testing in prostate cancer, depending on sample availability and if the testing is performed for somatic or germline mutations, and each approach comes with some advantages and limitations.

3.

The Testing Process

International guidelines recommend testing for HRR mutations in prostate cancer. Testing approach can be focused on single genes or HRR panel testing.

4.

Reporting Results

Biomarker test results should be reported in a concise, clear and standardized manner.